Was your family one of those that kept heading west every few years, leaving family behind in numerous locations? Have you searched for other relatives in those "left behind location?" If your ancestor left Amherst County, Virginia, in 1801 your research in Amherst County should not stop in 1801. There might be other family members left behind whose records provide clues about your direct line ancestors. There might even be descendants in the area today who could provide research help.